A level shifter includes a first level shift module for producing a shifted signal by adjusting a direct current level of an input signal by a first bias voltage having a first polarity. A voice mail filtering controller calculates a separate Bayesian score for each voice mail message from among multiple voice mail message entries received into a voice mailbox for a user, wherein each separate Bayesian score indicates a probability that the associated voice mail message is unwanted by said user. For forming two wire groups, a plurality of coil windings are simultaneously created by winding up n parallel wires with intermediate spacing onto a striplike former that is rotatable about its longitudinal axis. If there has been a change, the PHY is directed to reset a port to correspond to the appropriate transmission connection. These improvements include, among others, the use of mass labeling in luminescence polarization assays, diffusion enhancements in luminescence resonance energy transfer assays, and labeled andor unlabeled particulates in various luminescence assays.