The present invention comprises methods and compositions for delivery devices More particularly, the present invention comprises methods and compositions for devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide having oxygen and optionally active agents incorporated therein. A phase-locked loop adjusts a ratio of the frequency of the high frequency clock signal to the low frequency clock signal by adjusting the frequency of the high frequency clock signal. Also included is a multiplexer that is configured to receive the second output signals and has an output coupled to an input of the synchronous counter. In some embodiments, transmitters may include one or more antennas connected to at least one radio frequency integrated circuit and one microcontroller. The invention also provides, in part, polyhydroxylated bile acids for stimulating bile flow. The force transfer is preferably formed from Bowden cables.