In one exemplary embodiment, an automated medication preparation system including automated syringe preparation that involves reconstitution of the medication is provided. One portion and pressure reduced refrigerant exchanges heat in a cooler with refrigerant present between the first and third pressure reducing mechanisms, and another portion and pressure reduced refrigerant is evaporated by an evaporator. Devices implementing the above methods are also disclosed. Statistical and comparative data and reports including such and other information indicate a quality of care and provide epidemiologically cogent information. A multi-voltage level semiconductor device is provided whereby increases in the number of manufacturing steps can be restricted and decline in the performance of MOS transistors for use in low-voltage circuits can be suppressed.