An I2C MUX with an anti-lock device comprises an I2C multiplexer and a reset unit. The plastics do not adhesively or chemically bond to each other. At least one releasable fastener is provided for releasably securing the first end to the second end in order to secure the cincture to the waist. The invention provides for methods of modulating the immunostimulatory response to gene delivery by modifying the plasmid delivered to the cell. If an event occurs, the amplifier protection circuit is re-configured and the amplifier continues to operate with a second protection threshold in a second state. For example, the exercise system is used with a remote trainer to enhance exercise performance, with a remote medical professional for rehabilitation, andor with a competitor in a competition, such as in a powerweightlifting competition or in a video game.