The invention provides for an in-line network connection control device that controls the physical and logical connectivity of Ethernet attached end devices, switches or routers. The spiral pattern is an Archimedean spiral pattern or a parabolic spiral pattern. Examples of such steroid derivatives are -5-androstene-17-ol, androstane-17-ol-pregnane-17-ol or pregnane-17-ol derivatives. In some embodiments, the plunger includes extensions configured to couple the plunger to a drive assembly of a needle-free injection device.