An electrokinetic delivery system for personal use in self-administration of a medicament to a treatment site on an individual includes a device shaped to conform with the shape of a portion of an individual’s finger from a tip thereof to a location past the first finger joint. In various embodiments, the invention combines native or depletion mode metal-oxide-semiconductor transistors with the conventional enhancement mode n-channel and p-channel transistors in the design of the input buffer. Ions are transported from the first volume to the second volume through the channel under an electric field produced by the first and second electrode.