In a magnetic resonance scanner, a main magnet system is wound to generate a longitudinally directed main magnetic field at least in a scanning region. A photodiode further comprises a voltage source being capable to apply a variable voltage between the first doping region and the lightly doped layer of the second doping region in order to vary the expansion of a space charge zone of the p-n junction. The memory stores instructions that are executable to generate a number of synthetic frames, and insert the number of synthetic frames into a stream of data frames, the synthetic frames being transmitted to a responder endpoint address designated in the synthetic frames. The method may also include proving for activation circuitry connected to the first winding and the second winding. The invention is also cosmetic or therapeutic compositions comprising one or more such double-stranded oligoribonucleotide and methods of treatment by use thereof. A current sampling module samples a pump current signal to form a sample prior to an end of the drive signal.