The present invention features a method for producing fine spotted arrays of molecules comprising the following steps of immobilizing affinity anchors onto the array; preparing molecules of interest having affinity for the anchors; contacting the molecules of interest with the array; and washing the array to remove unbound molecules of interest. In addition to the foregoing, other method aspects are described in the claims, drawings, and text forming a part of the present disclosure. The polarization may be adjusted. The conductor ends are each applied electrically to a contact receiving device through the medium of an electrically conductive and elastically resilient material. These 6,9-disubstituted purine derivatives and their pharmaceutically acceptable salts are useful in compositions for application to mammalian cells, and especially human skin cells, in order to improve the cosmetic appearance of the mammalian cells, especially human skin. A linear mapping matrix corresponding to the LFSR to generate the CRC is planning, and the computation of the LFSR to the input message for the CRC generation becomes a simplified matrix multiplication.