In an SOI substrate having a semiconductor layer formed on the semiconductor substrate via an insulating layer, a MISFET is formed in each of the semiconductor layer in an nMIS formation region and a pMIS formation region. In the training phase, an optical system is represented by a point-spread function. The air plenum has an outlet that communicates the nonflammable premix of pressurized gases to the burner for combustion. Suitable matrix materials are materials to which cells can adhere, such as a gel made from collagen type I.