A measurement device according to one aspect of the present invention includes a first controller configured to output a control signal and a second controller configured to perform a first control and then to perform a second control based on the control signal output from the first controller. The invention further relates to macromolecules obtainable by a method of the invention. A dummy pattern is formed in the structural portion to reduce a difference between a sensitivity of a first pixel and that of a second pixel, which is produced by a difference between a structure in a periphery of the light waveguide arranged above the photoelectric converter of the first pixel and that of the second pixel. The control elements, are arranged to perform, firstly, a simulation process related to the gear selection strategy with at least one alternative set of parameters and, secondly; a comparative analysis based on a first set of control parameters.