An audio device performs self calibration with respect to an audio source location when processing an audio signal frame determined likely to be dominated by the audio source. The system and method further assigns a numerical cipher to each byte line and searches a position of each numerical cipher in a corresponding byte line. The curvature correction circuitry is coupled to the reference circuit output and comprises at least one additional complementary to temperature component. The composite gate structure is aligned with a blister of the blister pack to provide a child resistant barrier to an item contained therein. The detection systems and methods are designed to reliably and accurately detect the existence of the plasma unconfinement condition in a process-independent and recipe-independent manner.