A microtiter plate-based assay method requiring no radioactivity and that enables automated assays of DNA oxidative stress. Both sides of the traffic sign holder removably accept traffic signs which contain traffic control instructions. The CNIBP monitor calculates an estimated blood pressure that is supplied to the NIBP monitor. The contact further includes at least one insulating layer formed directly on the silicide layer. Projecting portions of fins are disposed between the projecting portions of the adjacent first heat exchange tubes.