The present invention has for an object agents for the simultaneous brightening and coloring of keratin fibers\u2014particularly hair\u2014which are characterized in that they contain an oxidant and at least one thiazolium dye of formula and that they have a basic pH . The second plate includes a second main body, and two slide rails positioned on two end of the second main body. The invention further relates to methods for generating eukaryotic host cells for expression of a gene product of interest, wherein these nucleic acid constructs are used, and to methods for producing a gene product of interest wherein thus generated host cells are applied.