GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The temperature sensor includes a sampling circuit coupled to receive a clock signal that samples the output signals for a duration of a predetermined number of clock cycles. When the material with a constant width is being rolled, axial positions of the work rolls are set at appropriate positions and axial positions of the intermediate rolls are changed to control a thickness distribution in a width direction of the material being rolled. A heat-radiating part of this semiconductor unit projects at the side of air inlet port of airflow passage. The segment assembly is bonded in the solid state at a combination of temperature, pressure, and time effective to produce a metallurgical joint between the first and second segments, thereby forming an intermediate article; and the intermediate article is heat treated to form a bonded article. Alternatively, the antenna return loss on the avoided frequencies is interpolated from the measured frequencies.