A replay attack from an unauthorized user is easily avoided by wireless communication authentication. The first wire rope connector includes a base defining a chamber for receiving an end of a first wire rope, a plug, and a cap that secures to the base to compress the plug and first wire rope end within the chamber. The device further is provided with guidewire tracking means. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure.