A stacked bed catalyst system comprising at least one first catalyst selected from conventional hydrotreating catalyst having an average pore diameter of greater than about 10 nm and at least one second catalyst comprising a bulk metal hydrotreating catalyst comprised of at least one Group VIII non-noble metal and at least one Group VIB metal and optionally a binder material. The compounds are of the general formula A representative example is: . The invention also provides for growth-inhibiting immunoliposomes that lack growth-inhibiting therapeutic agents and yet are capable of inhibiting the growth and proliferation of target cells. DCT filters are applied to the DCT coefficients of each macroblock to generate up-sampled macroblocks for each macroblock, there is one up-sampled macroblock generated by each filter.