Detection of toxic gluten oligopeptides refractory to digestion and antibodies and T cells responsive thereto can be used to diagnose Celiac Sprue. The first base plate and the second base plate separately have an inner surface and the second base plate is located with its inner surface opposite to the inner surface of the first base plate. The additional layer of material contains one or more cut through andor cut out void configurations that forms a breaking pattern that turns the additional layer into a break and tear template layer.