The present invention relates to a method of preventing, treating, or managing a condition of an animal, such as a mammal. The transmission control unit has a shift map for determining the gear depending on the vehicle speed and the accelerator opening degree of the engine, and, further, has a mode-judging means for judging an acceleration mode period and a deceleration mode period depending on the operating conditions of an accelerator pedal and a brake pedal. Automatic computer monitoring by one or a plurality of programmed redundant digital motor management computer or autopilot controls each motor-controller and motor to produce pitch, bank and elevation, while simultaneously restricting the flight regime that the pilot can command. In some embodiments, at least some direct offset connections connect pairs of nodes that are separated by more than one row and at least one column, or by more than one column and at least one row.