The method of estimating the relevance of a document with respect to a concept comprises calculating a relevance function of the concept with respect to said document on the basis of a known predetermined semantic neighborhood of the concept. Also provided is a method for producing mature dendritic cells in culture from the proliferating dendritic cell precursors. A thickness W of the base layer can be determined by:W=Vbd+Vpt4010\ue89e\ue89ekV\ue89e\ue89ecm-58*18wherein a punch-through voltage Vpt of the semiconductor device is between 70% and 99% of a break down voltage Vbd of the semiconductor device, and wherein the thickness W is a minimum thickness of the base layer between a junction to the channel region and the buffer layer. The one or more activity sensors can be configured to be positioned on an activity device, to detect operational indicators relative to the usage of the activity device and to transmit signals indicative of such operational indicators. The pattern on the decal is printed on the rubber plate. The stripper device is driven to move a note engaged therewith at a faster rate or for a longer time period relative to a note engaged with the picker device to reorient returning notes to facilitate a subsequent note separation attempt.