Semiconductor devices having conductive lines with extended ends and methods of extending conductive line ends by a variable distance are disclosed. The nanoparticulate posaconazole particles of the composition have an effective average particle size of less than about 2000 nm and are useful in the prevention and treatment of fungal infection and related diseases. In addition, the hood may be configured to incorporate an internal valve or baffle to create a watertight closure. The electrolysis process is continuously conducted until a second graphene oxide is exfoliated from the first graphene oxide, wherein the second graphene oxide has a size which is smaller than the pore size of the semipermeable membrane to penetrate through the semipermeable membrane.