The use of a lignan, which is a plant lignan, a metabolite thereof or a combination of both, for the manufacture of a composition for preventing or alleviating of symptoms relating to estrogen deficiency in an individual. A first set selectively connects predetermined IO contacts of each module interconnected to contacts of other modules, a second set selectively connects predetermined IO contacts of each module to the IO ports and a common test bus, and a third set applies the last logic state on each IO contact before isolation by a buffer from the first set. The CPUs may be programmed to generate respective data retrieving commands when the EEPROM is not being accessed for data retrieval.