A self-powered \u2018near field\u2019 lithographic system 100 includes three primary components, namely, a thin film or emitter substrate 110 including a radioactive material, a target substrate 120 which carries an energy-modifiable layer 122 and a stencil that is either positioned between the emitter and target substrates fabricated upon and defined in the emitter substrate. The foam body has a foam matrix of interconnected foam cells with cell walls which have incorporated therein a combination of inorganic antimicrobials as active agents, the active agents being incorporated into the foam matrix both topically on a foam cell surface and integrally within the foam cell wall. Arrangements for effective priming and pre-compression of liquid are also described. An open nano-structure, is formed in a substrate.