A substrate comprises a substrate main body having a surface on which a measurement object article is to be formed. The startup circuit injects high current into devices to start a reference circuit. A front side of the main body faces away from the child and includes a representation of a decorative character. The connecting end is in the form of a spigot fittable in a socket of the connectable device. The cross member is defined by a length and has a shell element extending over a major part of the length of the cross member, wherein the shell element has incorporated therein at least one deep-drawn reinforcement member of cup shape configuration. Also disclosed are nucleic acids such as siRNA, antisense, and enzymatic nucleic acid molecules that can modulate the expression of HIV env genes and HIV viral replication.