An electrostatic discharge device is described, including a gate line, a source region at a first side of the gate line, a comb-shaped drain region disposed at a second side of the gate line and having comb-teeth parts, a salicide layer on the source region and the drain region, and contact plugs on the salicide layer on the source region and the drain region. An assigned MPA approach path to an arrival runway is received at the aircraft. The present invention further includes analogs and derivatives of these polypeptides having VEGF antagonist activity.