The invention relates to combined agents comprising cis-hydroxyproline and gemcitabine and to the use of said agents in tumor prophylaxis and therapy. The sensor configuration includes a sensing element configured to receive a biasing voltage which creates an electric field from the sensing element to the ink drop generator. The cover plate defines a cover aperture which receives the middle member of the insert piece from a back side of the cover plate. The cold plate is secured to the structural member by a braze material.