The present invention comprises one or more microprocessors programmed to execute methods for improving the performance of an analyte monitoring device including prediction of glucose levels in a subject by utilizing a predicted slower-time constant. The photolytic artificial lung converts water to oxygen for blood absorption, regulates pH, the removes carbon dioxide, and co-produces electrical power is disclosed. Consequently, there has existed a problem that it is impossible to enhance the microscopic-defect detection sensitivity further than that. The event related choices may be generated based on campaigns by Promotional Agents.