The present invention provides a compound of formula I and the use thereof in the therapeutic treatment of disorders related to or affected by the 5-HT6 receptor . The foundation base has the opposite ends of one side respectively and longitudinally bored with a slide groove, provided with a fixing hole and a position-limiting pin at proper locations. Fuel is introduced briefly into at least one of the shut off cylinders and combusted in an at least essentially torque-neutral way during the cylinder shut off period. A second excitation to apply to the conduit is determined from the determined first excitation, the determined motion in response to the first excitation, a desired motion for the conduit, and a frequency response for the conduit.