Formulations for the administration through pressurized metered dose aerosol inhalers containing an anticholineric drug in solution in a hydrofluorocarbon propellant, a cosolvent and a low volatility component, and the use thereof in chronic obstructive pulmonary disease. The sub-matching block includes: a series matching block of which one end is connected to the main-matching block; and a parallel matching network connected to the other end of the series matching block. 2%, total titanium calculated as TiO2: from 0. One or more hook-shaped engaging tabs also protrude from the base portion. In another embodiment, the vacuum system is determined to be leaky if at least one of a series of pressure measurements exceeds the threshold pressure value. Serum phosphorus concentrations of the patient can then be predicted at any time during any hemodialysis treatment session with the estimated phosphorous mobilization clearance and pre-dialysis distribution volume of phosphorus of the patient.