Disclosed herein are R-7–1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8naphthyridine-3-carboxylic acid and L-aspartic acid salt, process for the preparation thereof and pharmaceutical composition comprising the same for antimicrobial. A photochromic dye can include a first photo-reactive group and a second photo-reactive group. An absorber layer is formed on the intermediate layer to absorb the EUV light The intermediate layer is formed by a material containing Cr and at least one element selected from the group consisting of N, O, and C. The broadcasting of the digital television and delivery the interactive broadband service occur simultaneously. The compounds are inhibitors of PI3K andor mTor and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.