Inner and outer shield parts of a breastshield are joined to form an enclosure defining a pressurizable chamber. Particular embodiments concern polycyclic alkaloids having a fused, six-membered ring, while other embodiments concern polycyclic alkaloids having a fused, five-membered ring. The mobile communication device may also include a location-determining component for determining geographic locations of the device and for transmitting location data to the portable computer.