The present invention provides binding moieties for fibrin, which have a variety of uses wherever detecting, isolating or localizing fibrin, and particularly fibrin as opposed to fibrinogen, is advantageous. When a user indicates that the user is attempting to or intending to open the file, the file can then be locked for editing. After the parameter conversion andor the reference value replacement, the parameters are provided as a part of assistance data for the satellite based positioning. The semiconductor substrate is disposed on the semiconductor substrate mounting part so that the detector comes close to the first conductor. The funnel cap includes a selectively operable valve. The controller includes logic for evaluating the performance of an operational circuit based on data obtained from process monitor module and operational circuit related data stored in a memory.