A universal bicycle rack with a lifting mechanism comprises a vehicle hitch-mounted bicycle carrier with mechanical vertical adjustment capabilities, a bicycle rack and a crank assembly. In particular, by intelligently managing reads and writes on a bi-directional bus, bus latency can be reduced while still ensuring no bus contention or readwrite starvation. For the use, the message is transmitted to a secured module that decrypts it, checks its compliance with an internal reference, and generates a digital accreditation controlling the unlocking of a lock device. The commission management system further comprises a payment processor for effecting commission payments to the members or to a designated sponsor on a scheduled basis. The second execution unit executes a second request received by the second request processing unit when the first device is in the active state, and executes the second request stored in the storage unit when the notification is received by the notification receiving unit. Methods of treating and moderating one or more bipolar disorders in a mammal are also provided.