A method of hybridizing a first nucleic acid to a second nucleic acid at least partially complementary to the first nucleic acid by providing a sample vessel and pressure controller for the vessel; and contacting the first and second nucleic acids within the vessel at a pressure above ambient pressure that is effective to enhance hybridization of the first and second nucleic acids. The resonating unit includes a first resonating unit connected to the transmission path and a second resonating unit having one end connected to the first resonating unit and another end short-circuited to the ground, the second resonating unit having terminals of the coupling electrode connected thereto. A computer connected to the transducers is connected to other computers via the Internet for enabling dental data exchange. According to the invention, the counterweight in the hand-held tool is supported so that it is able to move, in particular to reciprocate, coaxial or parallel to the translation axis. The user’s URL access policy may include an access deny or an access allow value which respectively denies or allows the user access to particular URL. The second lens system can be a cheap negative lens, and the invention is thereby particularly useful for increasing the field of view cheap, disposable optical probes.