A control signal MBPRG is inputted to individual block decoders that constitute a block decoder section 37 of an ACT type flash memory. Further provided are methods of making alphavirus particles comprising a recombinant nucleic acid of this invention and methods of using the compositions of this invention. Antibodies which bind Cripto and inhibit the interaction between Cripto and ALK4 andor between Cripto and Activin B are provided.