An image reading apparatus includes a light source unit, an image sensor, and a light guiding unit at least including a light reflector. The receivers capture signal strength data that is then transmitted to a processing location, which may be associated with a provider of the programming service. Recesses or apertures are formed within the baseplate and are located upon the first or second surfaces so as to define thermally activated optic mounting areas. The attached shutter components are separated into a plurality of prefinished shutter components, and the prefinished shutter components are incorporated into a shutter assembly. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.