The present invention provides new progesterone receptor modulators which are -8-fluorodibenzob,fpyrido1,2-doxazepine-1-amine compounds and uses thereof. The lens barrel changes a focal length by moving first and second lens groups in an optical axis direction. The assay of the present invention is readily adaptable for automation and permits the rapid through-put of samples to be tested. The GaN source is dissolved in a solvent and precipitates out of the solution as millimeter-scale single crystal filaments as a result of the applied temperature gradient. When the diffuse-noise-field detector detects diffuse noise, the filter coefficients of the adapted shadow filter is used by a primary filter to cancel the diffuse noise at the signal captured by the primary microphone. According to an optical connector of the present invention, a flat type optical fiber cable inserted into and secured in a ferrule is covered with the optical connector boot.