A refrigerator with an evaporator having a refrigerant pipe, and a defrosting heater placed below the evaporator and defrosting the evaporator, wherein the refrigerant pipe includes a main refrigerant pipe evaporating a refrigerant, and a heat-transfer refrigerant pipe extended from a lower part of the main refrigerant pipe so as to exchange heat, and disposed adjacent to the defrosting heater. The drinking cup is designed with thick and thin sections that extend vertically around the outside of the cup to provide sufficient rigidity and flexibility to allow it to operate as a drinking cup and as a cover that snaps on to and off from the top of a beverage can. Compositions and methods for the treatment of disorders related to leukocyte dysfunction or dysregulation are also provided. In this way, the aggregation operations are concatenated to local logic code for the aggregation operations. These components can be difficult to manufacture and can be expensive.