The present invention relates to substituted imidazopyridazines and substituted benzimidazoles, as well as pharmaceutical compositions comprising the same, which are FGFR3 inhibitors useful in the treatment of cancer and other diseases. The LMs of PE#1 to PE#n can be allocated to different areas of the memory space of PE#0 respectively, or can be allocated the same area thereof. A sealant is applied on the die at the conductive wires for preventing wire sweep and the sealant is free of contact with the interposer.