A road surface condition detection system capable of quickly and accurately detecting road surface conditions during vehicle running, an active suspension system and an anti-lock brake system using the road surface condition detection system, and a sensor unit for the road surface condition detection system are provided. The conferencing system further ensures that notifications are received at each of the participants so that each participant is able to synchronize its local display with the pace of a conferencing session. The enclosure is then sealed using a combination of covers, gaskets, o-rings, connectors and potting. An infilled particulate material is dispersed among the pile elements. Compounds of the invention are useful for the treatment of mammalian infertility.