A method for increasing the expression of SIRT1 mRNA andor decreasing the expression of SOCS3 mRNA, and especially for regulating blood glucose levels in a subject in need thereof is provided. In order to achieve particularly good treatment results, a cold medium, e. The system also includes a sponge disposed within the inner space defined by the housing. The IBMC determines whether the IBMC operates normally by detecting a voltage status of the GIPO pin. The semiconductor element provides a designated function in cooperation with a functional part of the resin housing.