An integrated optical device is disclosed comprising a substrate, optical waveguide, and compound optical resonator having a temperature sensor, at least two coupled optical resonators, and a heater localized to each optical resonator. The CD30-L polypeptide binds to the receptor known as CD30, which is expressed on a number of cell types, among which are Hodgkin’s Disease tumor cells, large cell anaplastic lymphoma cells, adult T-cell leukemia cells, and a number of other malignant cell types. When high-speed response is required, the first differential amplifier circuit is activated. Consequently, the desired cooling andor cooling effect can be maintained while reducing energy consumption of the climate control system. The circuitry may function to disconnect the photovoltaic panel from the output of the electrical circuit.