Systems, methods and apparatus are provided through which coronary plaque is classified in an image and visually displayed using an iterative adaptive process, such as an expectation maximization process. To effect the attributes of the switching fabric, conditionally nonblocking components are used a building-blocks in an interconnection network which is recursively constructed. The system is based on the ability to temporally and spatially induce the expression of CRE recombinase which then binds to directly repeated lox sites flanking the transgene in question leading to the precise excision of the gene cassette.