The invention relates to a hotmelt adhesive based on at least one ethylene andor propyleneC4 to C20 \u03b1-olefin copolymer obtainable by metallocene-catalysed polymerization, on at least one tackifying resin, and on at least 0. Cathelicidin and defensin homologs from a variety of species exhibit broad-range bactericidal activity. Additionally, the thermostatic biasing controller also includes a voltage controlling unit coupled to the temperature sensing unit and configured to provide a back-bias voltage corresponding to the operating temperature based on reducing a quiescent current of the integrated circuit.