A part of a toner supply path is formed in a setting unit, and a nozzle coupled to a toner container is provided, wherein the fitting direction of the toner container to the setting unit and the coupling direction of the nozzle to the toner container are different. In addition, the invention provides a variety of prescreening and screening methods aimed at identifying agents that modulate a drug-related effect or behavior. The compression plate is connected to the mount so that the compression plate is rotatable relative to the subject table in the longitudinal and transverse directions of the plate.