This invention provides novel heterocyclic derived matrix metalloprotease inhibitors of the formula:and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing matrix metalloproteases. The liquid crystal display device includes a backlight configured to emit light toward a liquid crystal panel and a microlens array interposed between the liquid crystal panel and the backlight. Further, weather information is identified for a predicted flight trajectory of an aircraft from the obtained on-board weather information. In another embodiment the piezoelectric igniter forms part of the electrical circuit and is in electrical conductive contact or proximity to an electrical conductor that forms part of the ignition circuit. The metal source material and the reducing agent may be fed continuously or in pulses during the deposition process.