Provided are a scanning probe microscope that prevents a distortion of an image caused by alignment errors of scanners and a method of measuring a sample using the same. Only the least significant bytes of the current trace address that do not match the comparison address or are less significant than any section of the current trace address that does not match the comparison address are transmitted. The first plate portion has a first knurled region on a first side disposed proximate to the ultrasonic horn, and the second plate portion has a second knurled region on the first side. The nucleic acid-coated particles bombard this mixture, and a transformed plant is produced. Edge electrodes connected to the first electrode layers at the edges of the slits, respectively, are formed on respective edges at the slits of the substrate. Methods of the invention include using die-to-die comparison to identify bright portions of scattering patterns and generate unique image filters associated with those patterns.