A method of designing a logic circuit includes providing a leaf cell having at least one transistor. Accordingly, the amino acid sequence of S16AhTERT and nucleic acid sequences encoding same are presented herein, as are methods of use thereof. Based on the optical input signals, the nonlinear element generates an optical output signal having a binary logic level. The locking device can be a cinching, ratcheting or clamping device, or a combination thereof, on the actuator device.