Methods and apparatuses provide noise reduction in a demosaiced digital image by processing the digitized signals received from a color pattern pixel array for noise reduction previous to, or as part of, a demosaicing process by using a weight matrix. Performance monitoring circuitry generates a performance monitoring signal corresponding to a detected performance level of selected digital operations of the powered component relative to a reference performance level. A preferred embodiment is a method of lowering intraocular pressure using 5–N-acetyltryptamine, also known as GR 135531, which has a prolonged duration of action and greater efficacy in lowering intraocular pressure compared to melatonin. The temperature of the crystallization unit is at least 80\xb0 C. A self-validation method for use by a computer is also disclosed. Then 3D graphic images are displayed in the 2D environments by using the encoded geometry for reconstructing a portion of, or all, the remaining polygons and filling the remaining polygons according to predefined rules.