A method for the optimization of radiation therapy treatment plans is disclosed. This effect is achieved by forming a poly interlayer that has a relatively stiff poly inner layer disposed between two relatively soft outer poly layers, where the stiffness difference is achieved by a plasticizer differential that is achieved at least in substantial part by a residual hydroxyl content difference among the poly layers. The at least one on-chip processor determined, within said transceiver chip, a frame size of at least one audio frame comprising the compressed audio information. An interlayer dielectric is positioned over the memory line and the inactive area, and an extending member extends through the interlayer dielectric. A modified artificial vessel is also disclosed, wherein the adherence of endothelial cells is enhanced by coating a genetically engineered CBD-RGD containing peptide layer on the inner surface of the artificial vessels pre-modified by cross-linked gelatin, and the adhering capacity and activation of platelets is reduced.