In a fluid mixing apparatus and a fluid mixing system including the apparatus, a micro-reactor has a plate sandwiched by a lid member and a receiving member. The techniques may include determining a metamodel indicating relationships between objects, and determining rules for obscuring data about the objects of the metamodel. Peptides including the domain and nucleotides encoding the domain are useful in molecular screening of human tumors for the presence of mutations that allow proliferation of cells that were otherwise marked for apoptosis. In yet another embodiment, the support device is further provided with a pump attached to the bleed valve.